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Eunice Kennedy Shriver National Institute of Child Health and Human Development, Laboratory of Genomic Integrity
National Institute of Child Health and Human Development
Division of Intramural Research

Publications

2006-2007

Yang W, Woodgate R. What a difference a decade makes: insights into translesion DNA synthesis. Proc Natl Acad Sci U S A. 2007; 104: 15591-8.  

d'Abbadie M, Hofreiter M, Vaisman A, Loakes D, Gasparutto D, Cadet J, Woodgate R, Pääbo S, Holliger P. Molecular breeding of polymerases for amplification of ancient DNA. Nat Biotechnol. 2007; 25: 939-43. 

Frank EG, Woodgate R. Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese. J Biol Chem. 2007; 282: 24689-96.

Wang Y, Woodgate R, McManus TP, Mead S, McCormick JJ, Maher VM. Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase eta, DNA Polymerase iota Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations. Cancer Res. 2007; 67: 3018-26.

Mead S, Vaisman A, Valjavec-Gratian M, Karata K, Vandewiele D, Woodgate R. Characterization of polVR391: a Y-family polymerase encoded by rumA'B from the IncJ conjugative transposon, R391. Mol Microbiol. 2007; 63: 797-810. 

Schlacher K, Cox MM, Woodgate R, Goodman MF. RecA acts in trans to allow replication of damaged DNA by DNA polymerase V. Nature. 2006; 442: 883-7. 

Schlacher K, Jiang Q, Woodgate R, Goodman MF. Purification and characterization of Escherichia coli DNA polymerase V. Methods Enzymol. 2006; 408:378-90. 

Plosky BS, Vidal AE, de Henestrosa AR, McLenigan MP, McDonald JP, Mead S, Woodgate R. Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin. EMBO J. 2006; 25:2847-55. 

McDonald JP, Hall A, Gasparutto D, Cadet J, Ballantyne J, Woodgate R.Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs. Nucleic Acids Res. 2006; 34:1102-11. 

Martomo SA, Yang WW, Vaisman A, Maas A, Yokoi M, Hoeijmakers JH, Hanaoka F, Woodgate R, Gearhart PJ. Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota. DNA Repair. 2006; 5:392-8.

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