2002 - 2003
Shen X, Woodgate R, Goodman MF. Escherichia coli DNA polymerase V subunit exchange: a post-SOS mechanism to curtail error-prone DNA synthesis. J Biol Chem. 2003 Dec 26;278(52):52546-50.
Vaisman A, Frank EG, Iwai S, Ohashi E, Ohmori H, Hanaoka F, Woodgate R. Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota. DNA Repair (Amst). 2003 Sep 18;2(9):991-1006.
McDonald JP and Woodgate R. Letter to the Editor. DNA Repair, 2003; 2:1159-1160.
McDonald JP, Frank EG, Plosky BS, Rogozin IB, Masutani C, Hanaoka F, Woodgate R, Gearhart PJ. 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation. J Exp Med. 2003 Aug 18;198(4):635-43.
Ling H, Boudsocq F, Plosky BS, Woodgate R, Yang W. Replication of a cis-syn thymine dimer at atomic resolution. Nature. 2003 Aug 28;424(6952):1083-7.
Prasad R, Bebenek K, Hou E, Shock DD, Beard WA, Woodgate R, Kunkel TA, Wilson SH. Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. J Biol Chem. 2003 Aug 8;278(32):29649-54.
Goodman MF, Woodgate R. The biochemical basis and in vivo regulation of SOS-induced mutagenesis promoted by Escherichia coli DNA polymerase V (UmuD'2C). Cold Spring Harb Symp Quant Biol. 2000;65:31-40. Review.
Kannouche P, Fernandez de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR. Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J. 2003 Mar 3;22(5):1223-33.
Boudsocq F, Ling H, Yang W, Woodgate R. Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass. DNA Repair (Amst). 2002 May 30;1(5):343-58.
Frank EG, Sayer JM, Kroth H, Ohashi E, Ohmori H, Jerina DM, Woodgate R. Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota. Nucleic Acids Res. 2002 Dec 1;30(23):5284-92.
Vaisman A, Frank EG, McDonald JP, Tissier A, Woodgate R. poliota-dependent lesion bypass in vitro. Mutat Res. 2002 Dec 29;510(1-2):9-22.
Pham P, Seitz EM, Saveliev S, Shen X, Woodgate R, Cox MM, Goodman MF. Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11061-6.
Borden A, O'Grady PI, Vandewiele D, Fernandez de Henestrosa AR, Lawrence CW, Woodgate R. Escherichia coli DNA polymerase III can replicate efficiently past a T-T cis-syn cyclobutane dimer if DNA polymerase V and the 3' to 5' exonuclease proofreading function encoded by dnaQ are inactivated. J Bacteriol. 2002 May;184(10):2674-81.
Rangarajan S, Woodgate R, Goodman MF. Replication restart in UV-irradiated Escherichia coli involving pols II, III, V, PriA, RecA and RecFOR proteins. Mol Microbiol. 2002 Feb;43(3):617-28.
Kokoska RJ, Bebenek K, Boudsocq F, Woodgate R, Kunkel TA. Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. J Biol Chem. 2002 May 31;277(22):19633-8.
Gonzalez M, Woodgate R. The "tale" of UmuD and its role in SOS mutagenesis. Bioessays. 2002 Feb;24(2):141-8. Review.
Vandewiele D, Fernandez de Henestrosa AR, Timms AR, Bridges BA, Woodgate R. Sequence analysis and phenotypes of five temperature sensitive mutator alleles of dnaE, encoding modified alpha-catalytic subunits of Escherichia coli DNA polymerase III holoenzyme. Mutat Res. 2002 Jan 29;499(1):85-95.
Shen X, Sayer JM, Kroth H, Ponten I, O'Donnell M, Woodgate R, Jerina DM, Goodman MF. Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts. J Biol Chem. 2002 Feb 15;277(7):5265-74.